Publications

67. González-Buenfil R, Vieyra-Sánchez S, Quinto-Cortés CD, Oppenheimer SJ, Pomat W, Laman M, (...Moreno-Estrada, A.). (2024). Genetic Signatures of Positive Selection in Human Populations Adapted to High Altitude in Papua New Guinea. GBE [link]

66. Chong AY, Brenner N, Jimenez-Kaufmann A, Cortes A, Hill M, (...Moreno-Estrada, A.). (2024). A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy. Mol Ecol. [link]

65. Sohail M & (...Moreno-Estrada, A.). (2024). The Mexican Biobank Project promotes genetic discovery, inclusive science and local capacity building. Dis Model Mech. [link]

64. Sohail M, Palma-Martínez MJ, Chong AY, Quinto-Cortés CD, Barberena-Jonas C, (...Moreno-Estrada, A.). (2023). Mexican Biobank advances population and medical genomics of diverse ancestries. Nature. [link]

64. Medina-Muñoz SG, Ortega-Del Vecchyo D, Cruz-Hervert LP, Ferreyra-Reyes L, García-García L, (...Moreno-Estrada, A.), Ragsdale AP. (2023). Demographic modeling of admixed Latin American populations from whole genomes. Mol Ecol. [link]

64. Nigenda-Morales SF, Lin M, Nuñez-Valencia PG, Kyriazis CC, Beichman AC, Robinson JA, (...Moreno-Estrada, A.), Wayne RK. (2023). The genomic footprint of whaling and isolation in fin whale populations. Nat Commun. [link]

63. Huerta-Chagoya A, Schroeder P, Mandla R, Deutsch AJ, Zhu W, Petty L, (...Moreno-Estrada, A.). (2023). Mexican Biobank; Aguilar-Salinas CA, Tusié T, Dupuis J, Ng MCY, Manning A, Highland HM, Cnop M, Hanson R, Below J, Florez JC, Leong A, Mercader JM. The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes. Diabetology. [link]

62.Beichman AC, Robinson J, Lin M, (...Moreno-Estrada, A.), Nigenda-Morales S, Harris K. (2023). Evolution of the Mutation Spectrum Across a Mammalian Phylogeny. Mol Ecol. [link]

61. Beichman AC, Kalhori P, Kyriazis CC, DeVries AA, Nigenda-Morales S, Heckel G, Schramm Y., (...Moreno-Estrada, A.), Kennett DJ, Hylkema M, Bodkin J, Koepfli KP, Lohmueller KE, Wayne RK. (2023). Genomic analyses reveal range-wide devastation of sea otter populations. Mol Ecol. [link]

60. Villa-Islas, V., Izarraras-Gomez, A., Larena, M., Campos, E. M. P., Sandoval-Velasco, M., Rodríguez-Rodríguez, J. E., (...Moreno-Estrada, A.) & Ávila-Arcos, M. C. (2023). Demographic history and genetic structure in pre-Hispanic Central Mexico. Science. [link]

58. Sohail M., Chong A., Quinto-Cortés C., Medina S., Barberena C., Ferreyra L., (...), Novembre J., Garcia-Garcia L., Moreno-Estrada A. (2022). Nationwide genomic biobank in Mexico unravels demographic history and complex trait architecture from 6,057 individuals. BioRxiv. [link]

57. Caro-Consuegra, R., Nieves-Colón, M. A., Rawls, E., Rubin-de-Celis, V., Lizárraga,B., Vidaurre, T., (...Moreno-Estrada, A.) & Bosch, E. (2022). Uncovering signals of positive selection in Peruvian populations from three ecological regions. Molecular Biology and Evolution. [link]

56. Liu, Y. C., Hunter-Anderson, R.,Cheronet, O., Eakin, J., Camacho, F.,Pietrusewsky, M., (...Moreno-Estrada, A.) & Reich, D.(2022). Ancient DNA reveals five streams of migration into Micronesia and matrilocality in early Pacific seafarers. Science. [link]

55. Nieves-Colón, M. A., Rivera, K. M. B., Sandoval, K., Dávalos, V. V., Lencinas, L. E. E., Mendoza-Revilla, J., ... & Moreno-Estrada, A. (2022). Clotting factor genes are associated with preeclampsia in high-altitude pregnant women in the Peruvian Andes. The American Journal of Human Genetics. [link]

54. Bastard, P., Hsiao, K. C., Zhang, Q., Choin, J., Best, E., Chen, J., (...Moreno-Estrada A.) & Casanova, J. L. (2022). A loss-of-function IFNAR1 allele in Polynesia underlies severe viral diseases in homozygotes. Journal of Experimental Medicine. [link]

53. Mendoza-Revilla, J., Chacón-Duque, J. C., Fuentes-Guajardo, M., Ormond, L., Wang, K., Hurtado, M., (...Moreno-Estrada A.), & Hellenthal, G. (2022). Disentangling signatures of selection before and after European colonization in Latin Americans. Molecular Biology and Evolution. [link]

52. Rodriguez-Rodriguez, J. E., Ioannidis, A. G., Landa-Chavarria, E., Blanco-Portillo, J., Quinto-Cortes, C. D., Penaloza-Espinosa, R. I., ... & Moreno-Estrada, A. (2022). The genetic legacy of the Manila Galleon trade in Mexico. Philosophical Transactions of the Royal Society B. [link]

51. Beichman, A. C., Kalhori, P., Kyriazis, C. C., DeVries, A. A., Nigenda-Morales, S., Heckel, G., ... & Wayne, R. K.(2021). Genomic analyses reveal range‐wide devastation of sea otter populations. Molecular Ecology [link]

50. Jiménez-Kaufmann, A., Chong, A. Y., Cortés, A., Fernandez-Valverde, S. L., Ferreyra-Reyes, L., Cruz-Hervert, P., ... & Moreno-Estrada, A.(2021). Imputation performance in Latin American populations: improving rare variants representation with the inclusion of Native American genomes. Frontiers in Genetics [link]

49. Ojeda-Granados C, Abondio P, Setti A, Sarno S, Gnecchi-Ruscone GA, González-Orozco E, De Fanti S, Jiménez-Kaufmann A, Rangel-Villalobos H, Moreno-Estrada A, Sazzini M.(2021). Dietary, Cultural and Pathogens-Related Selective Pressures Shaped Differential Adaptive Evolution Among Native Mexican Populations. Mol Biol Evol [link]

48. Rivera, K. M. B., Nieves-Colon, M. A., Mendoza, K. S., Davalos, V. V., Lencinas, L. E. E., Chen, J. W., ... & Moreno-Estrada, A. (2021). Clotting factor genes are associated with preeclampsia in high altitude pregnant women in the Peruvian Andes. medRxiv [link]

47. Ioannidis, A. G.,Blanco-Portillo, J.,Sandoval, K., Hagelberg, E., Barberena-Jonas, C., Hill, A. V., ... & Moreno-Estrada, A. (2021). Paths and timings of the peopling of Polynesia inferred from genomic networks. Nature [link]

46. COVID-19 Host Genetics Initiative (2021). Mapping the human genetic architecture of COVID-19. Nature [link]

45. Ioannidis, A. G., Blanco-Portillo, J., Sandoval, K., Hagelberg, E., Miquel-Poblete, J. F., Moreno-Mayar, J. V., ... & Moreno-Estrada A. (2020). Native American gene flow into Polynesia predating Easter Island settlement. Nature [link]

44. Ávila-Arcos, M. C., McManus, K. F., Sandoval, K., Rodríguez-Rodríguez, J. E., Martin, A. R., Luisi, P., Villa-Islas V, Peñaloza-Espinosa RI, Eng C, Huntsman S., Burchard EG., Gignoux CR., Bustamante CD., Moreno-Estrada A. (2019). Population history and gene divergence in Native Mexicans inferred from 76 human exomes. MBE [link]

43. Ongaro L., Scliar M.O., Flores R., Raveane A., Marnetto D., Sarno S., (… Moreno-Estrada A.,…) & Montinaro F. (2019). The genomic impact of European colonization of the Americas. Current Biology 29(23): 3974–3986. [link]

42. Wojcik, G. L., Graff, M., Nishimura, K. K., Tao, R., Haessler, J., Gignoux, C. R., (…Moreno-Estrada A.,…) & Carlson C.S. (2019). Genetic analyses of diverse populations improves discovery for complex traits. Nature 570(7762): 514-518. [link]

41. Gignoux, C. R., Torgerson, D. G., Pino-Yanes, M., Uricchio, L. H., Galanter, J., Roth, L. A., (…Moreno-Estrada A.,…) & Mathias, R. A. (2019). An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos. Journal of Allergy and Clinical Immunology 143(3):957-969. [link]

40. Huerta-Chagoya, A., Moreno-Macías, H., Fernández-López, J. C., Ordóñez-Sánchez, M. L., Rodríguez-Guillén, R., Contreras, A Hidalgo-Miranda A., Alfaro-Ruíz L.A., Salazar-Fernandez E.P., Moreno-Estrada A. and Aguilar-Salinas, C.A. (2019). A panel of 32 AIMs suitable for population stratification correction and global ancestry estimation in Mexican mestizos. BMC Genetics 20(1): 1-11. [link]

39. Mak, A. C., White, M. J., Eckalbar, W. L., Szpiech, Z. A., Oh, S. S., Pino-Yanes, (…Moreno-Estrada A.,…) & Esteban G Burchard, on behalf of the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. (2018) Whole Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma. Am. J. Respir. Crit. Care Med 6, e4512. [link]

38. De la Fuente, C., Ávila-Arcos, M.C., Galimany, J., Carpenter, M.L., Homburger, J.R., Blanco, A., Contreras, P., Dávalos, D.C., Reyes, O., San Roman, M. & Moreno-Estrada, A. (2018). Genomic insights into the origin and diversification of late maritime hunter-gatherers from the Chilean Patagonia. PNAS 201715688. [link]

37. Belbin, G. M., Nieves-Colón, M. A., Kenny, E. E., Moreno-Estrada, A., & Gignoux, C. R (2018). Genetic diversity in populations across Latin America: implications for population and medical genetic studies. Current opinion in genetics & development (53), 98-104 [link]

36. Nigenda-Morales, S. F., Harrigan, R. J., & Wayne, R. K. (2018). Playing by the rules? Phenotypic adaptation to temperate environments in an American marsupial. PeerJ 6, e4512. [link]

35. Nigenda‐Morales, S. F., Hu, Y., Beasley, J., Ruiz‐Piña, H. A., Valenzuela‐Galván, D., & Wayne, R. K. (2018). Transcriptomic analysis of skin pigmentation variation in the Virginia opossum (Didelphis virginiana). Molecular Ecology . [link]

34. Quinto-Cortés, C. D., Woerner, A. E., Watkins, J. C., & Hammer, M. F. (2018). Modeling SNP array ascertainment with Approximate Bayesian Computation for demographic inference. Scientific Reports 8(1), 10209. [link]

33. Nieves‐Colón, M. A., Ozga, A. T., Pestle, W. J., Cucina, A., Tiesler, V., Stanton, T. W., & Stone, A. C. (2018). Comparison of two ancient DNA extraction protocols for skeletal remains from tropical environments. American Journal of Physical Anthropology . [link]

32. Cruz-Dávalos, D. I., Nieves-Colón, M. A., Sockell, A., Poznik, G. D., Schroeder, H., Stone, A. C., ... & Ávila-Arcos, M. C. (2018). In-solution Y-chromosome capture-enrichment on ancient DNA libraries. BMC Genomics,19(1), 608. [link]

31. Belbin, G. M., Nieves-Colón, M. A., Kenny, E. E., Moreno-Estrada, A., & Gignoux, C. R. (2018). Genetic diversity in populations across Latin America: implications for population and medical genetic studies. Current Opinion in Genetics & Development,53, 98-104. [link]

30. Mallick, S., Li, H., Lipson, M., Mathieson, I., Gymrek, M., Racimo, F., ... & Skoglund, P. (2016). The Simons Genome Diversity Project: 300 genomes from 142 diverse populations. Nature. [link]

29. Alarcón‐Riquelme, M. E., Ziegler, J. T., Molineros, J., Howard, T. D., Moreno‐Estrada, A., Sánchez‐Rodríguez, E., ... & Kelly, J. A. (2016). Genome‐Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture. Arthritis & Rheumatology, 68(4), 932-943. [link]

28. Arteaga, M. C., Moreno-Letelier, A., Mastretta-Yanes, A., Vázquez-Lobo, A., Breña-Ochoa, A., Moreno-Estrada, A., ... & Piñero, D. (2016). Genomic variation in recently collected maize landraces from Mexico. Genomics Data, 7, 38-45. [link]

27. Homburger, J., Moreno-Estrada, A., Gignoux, C., Nelson, D., Sanchez, E., Ortiz-Tello, P., . . . Bustamante, C. (2015). Genomic Insights into the Ancestry and Demographic History of South America. PLOS Genetics, 1-26. doi:10.1371/journal.pgen.1005602 [link]

26. Raghavan, M., Steinrücken, M., Harris, K., Schiffels, S., Rasmussen, S., DeGiorgio, M., ... & Eriksson, A. (2015). Genomic evidence for the Pleistocene and recent population history of Native Americans. Science, 349(6250), aab3884. [link]

25. Pino-Yanes, M., Gignoux, C. R., Galanter, J. M., Levin, A. M., Campbell, C. D., Eng, C., ... & O'Roak, B. J. (2015). Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos. Journal of Allergy and Clinical Immunology, 135(6), 1502-1510. [link]

24. Pino-Yanes, M., Thakur, N., Gignoux, C. R., Galanter, J. M., Roth, L. A., Eng, C., ... & Nguyen, E. A. (2015). Genetic ancestry influences asthma susceptibility and lung function among Latinos. Journal of Allergy and Clinical Immunology, 135(1), 228-235. [link]

23. Moreno-Estrada, A., Gignoux, C., Fernandez-Lopez, J., Zakharia, F., Sikora, M., & Contreras, A. et al. (2014). The genetics of Mexico recapitulates Native American substructure and affects biomedical traits. Science, 344(6189), 1280-1285. http://dx.doi.org/10.1126/science.1251688 [link]

22. Sikora, M., Carpenter, M., Moreno-Estrada, A., Henn, B., Underhill, P., & Sánchez-Quinto, F. et al. (2014). Population Genomic Analysis of Ancient and Modern Genomes Yields New Insights into the Genetic Ancestry of the Tyrolean Iceman and the Genetic Structure of Europe. PLOS Genetics, 10(5), e1004353. http://dx.doi.org/10.1371/journal.pgen.1004353 [link]

21. Moreno-Estrada, A., Gravel, S., Zakharia, F., McCauley, J., Byrnes, J., & Gignoux, C. et al. (2013). Reconstructing the Population Genetic History of the Caribbean. PLOS Genetics, 9(11), e1003925. http://dx.doi.org/10.1371/journal.pgen.1003925 [link]

20. Gravel, S., Zakharia, F., Moreno-Estrada, A., Byrnes, J., Muzzio, M., & Rodriguez-Flores, J. et al. (2013). Reconstructing Native American Migrations from Whole-Genome and Whole-Exome Data. PLOS Genetics, 9(12), e1004023. http://dx.doi.org/10.1371/journal.pgen.1004023 [link]

19. Moreno-Estrada, A., & Sandoval, K. (2013). Diversidad genómica en México. Pasado indígena y mestizaje. Cuicuilco, 20(58), 249-276. [link]

18. Carpenter, M., Buenrostro, J., Valdiosera, C., Schroeder, H., Allentoft, M., & Sikora, M. et al. (2013). Pulling out the 1%: Whole-Genome Capture for the Targeted Enrichment of Ancient DNA Sequencing Libraries. The American Journal Of Human Genetics, 93(5), 852-864. http://dx.doi.org/10.1016/j.ajhg.2013.10.002 [link]

17. Kenny, E., Timpson, N., Sikora, M., Yee, M., Moreno-Estrada, A., & Eng, C. et al. (2012). Melanesian Blond Hair Is Caused by an Amino Acid Change in TYRP1. Science, 336(6081), 554-554. http://dx.doi.org/10.1126/science.1217849 [link]

16. Sandoval, K., Moreno-Estrada, A., Mendizabal, I., Underhill, P., Lopez-Valenzuela, M., & Peñaloza-Espinosa, R. et al. (2012). Y-chromosome diversity in Native Mexicans reveals continental transition of genetic structure in the Americas. Am. J. Phys. Anthropol., 148(3), 395-405. http://dx.doi.org/10.1002/ajpa.22062 [link]

15. Kidd, J. M., Gravel, S., Byrnes, J., Moreno-Estrada, A., Musharoff, S., Bryc, K., ... & McLaughlin, S. F. (2012). Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation. The American Journal of Human Genetics, 91(4), 660-671. [link]

14.Drake, K. A., Torgerson, D. G., Gignoux, C. R., Galanter, J. M., Roth, L. A., Huntsman, S., ... & Bustamante, C. D. (2014). A genome-wide association study of bronchodilator response in Latinos implicates rare variants. Journal of Allergy and Clinical Immunology, 133(2), 370-378. [link]

13.Kumar, R., Nguyen, E. A., Roth, L. A., Oh, S. S., Gignoux, C. R., Huntsman, S., ... & López-López, M. (2013). Factors associated with degree of atopy in Latino children in a nationwide pediatric sample: the Genes-environments and Admixture in Latino Asthmatics (GALA II) study. Journal of Allergy and Clinical Immunology, 132(4), 896-905. [link]

12. Antolin, M., Jenkins, K., Bergstrom, C., Crespi, B., De, S., & Hancock, A. et al. (2012). Evolution and Medicine in Undergraduate Education: A Prescription for All Biology Students. Evolution, 66(6), 1991-2006. http://dx.doi.org/10.1111/j.1558-5646.2011.01552.x [link]

11. Chen, R., Corona, E., Sikora, M., Dudley, J., Morgan, A., & Moreno-Estrada, A. et al. (2012). Type 2 Diabetes Risk Alleles Demonstrate Extreme Directional Differentiation among Human Populations, Compared to Other Diseases. PLOS Genetics, 8(4), e1002621. http://dx.doi.org/10.1371/journal.pgen.1002621 [link]

10. Henn, B., Botigué, L., Gravel, S., Wang, W., Brisbin, A., & Byrnes, J. et al. (2012). Genomic Ancestry of North Africans Supports Back-to-Africa Migrations. PLOS Genetics, 8(1), e1002397. http://dx.doi.org/10.1371/journal.pgen.1002397 [link]

9. Keller, A., Graefen, A., Ball, M., Matzas, M., Boisguerin, V., & Maixner, F. et al. (2012). New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing. Nature Communications, 3, 698. http://dx.doi.org/10.1038/ncomms1701 [link]

8. Moreno-Estrada, A., Aparicio-Prat, E., Sikora, M., Engelken, J., Ramírez-Soriano, A., Calafell, F., & Bosch, E. (2010). African signatures of recent positive selection in human FOXI1. BMC Evol Biol, 10(1), 267. http://dx.doi.org/10.1186/1471-2148-10-267 [link]

7. Bryc, K., Velez, C., Karafet, T., Moreno-Estrada, A., Reynolds, A., & Auton, A. et al. (2010). Genome-wide patterns of population structure and admixture among Hispanic/Latino populations. Proceedings Of The National Academy Of Sciences, 107(Supplement_2), 8954-8961. http://dx.doi.org/10.1073/pnas.0914618107 [link]

6. Henn, B., Gravel, S., Moreno-Estrada, A., Acevedo-Acevedo, S., & Bustamante, C. (2010). Fine-scale population structure and the era of next-generation sequencing. Human Molecular Genetics, 19(R2), R221-R226. http://dx.doi.org/10.1093/hmg/ddq403 [link]

5. Acuna-Alonzo, V., Flores-Dorantes, T., Kruit, J., Villarreal-Molina, T., Arellano-Campos, O., & Hunemeier, T. et al. (2010). A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans. Human Molecular Genetics, 19(14), 2877-2885. http://dx.doi.org/10.1093/hmg/ddq173 [link]

4. Moreno-Estrada, A., Tang, K., Sikora, M., Marques-Bonet, T., Casals, F., & Navarro, A. et al. (2009). Interrogating 11 Fast-Evolving Genes for Signatures of Recent Positive Selection in Worldwide Human Populations. Molecular Biology And Evolution, 26(10), 2285-2297. http://dx.doi.org/10.1093/molbev/msp134 [link]

3. Bosch, E., Laayouni, H., Morcillo-Suarez, C., Casals, F., Moreno-Estrada, A., & Ferrer-Admetlla, A. et al. (2009). Decay of linkage disequilibrium within genes across HGDP-CEPH human samples: most population isolates do not show increased LD. BMC Genomics, 10(1), 338. http://dx.doi.org/10.1186/1471-2164-10-338 [link]

2. Moreno-Estrada, A., Casals, F., Ramirez-Soriano, A., Oliva, B., Calafell, F., Bertranpetit, J., & Bosch, E. (2008). Signatures of Selection in the Human Olfactory Receptor OR5I1 Gene. Molecular Biology And Evolution, 25(1), 144-154. http://dx.doi.org/10.1093/molbev/msm240 [link]

1. Morcillo-Suarez, C., Alegre, J., Sangros, R., Gazave, E., de Cid, R., & Milne, R. et al. (2008). SNP analysis to results (SNPator): a web-based environment oriented to statistical genomics analyses upon SNP data. Bioinformatics, 24(14), 1643-1644. http://dx.doi.org/10.1093/bioinformatics/btn241 [link]